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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '9252df3f40094123d70caae4e23340e5ea951f6ec02c6fb6591054f507dbd329' 
  AND token = 'ANkFKWwm1+dwzDY11W/r2myFZ09bVNXgH45x9A2iOsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}