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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '486080e8c83e625c91e68d3dad686c9e23c2c09ed21029ab85836dda6bc08fe0' 
  AND token = 'wjFXuREcvAv/g0gbFy6O+LIMujJYs+0g+WbQqJGO9yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}