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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '5f5219efd00dd1b4aa505ed87e397b02a9918b841decfef738ef9fd3dc51b353' 
  AND token = 'a6LzqCfiVS7vFLqzdw6nKd+vEquhR1jXB/y/eqN0f6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}