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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '16f1894657d2a5cfc16336a07f937232446d31112db1dd1c0eb90e8fe9686067' 
  AND token = 'k6CjwR+VWuSTn3YUAx5wFlcCOoR4dhS6bcYtJGQORw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}