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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '22586a3791ba789f004886ee1dc97bbd3adcb4a4a0d3317c61eb5d6e360d5cbe' 
  AND token = 'b4wBPqbiMBDumHQOJckg115Xmu3Ye4kqb6c3LtDlDp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}