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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'e846b2186ada3cd24d808efecf3ca3c0a26341daeab8cba35f33142df02a4fe4' 
  AND token = 'V1lJZqz61VD/XyeD8OW5PzfhSiCGqmsrSNiskVu2HO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}