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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '123265f752371d4180e15c1293c919325be8383b21671c61cc0fb9bbccefd0ab' 
  AND token = 'Fbe9lpvvlO0CMQyF6R172427JBb/K+xhBaCr1S+Rn/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}