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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '101dab045967a6e1327bc267f10e0aaff5f297bfd6299772d3f2f421838b05c7' 
  AND token = '1mQagY486AwHeCg28zKZqWU+2TAUqfY0tFETvdDQP0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}