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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'd2d01a9d04b3b42745ec5d243b7a552fbd5d0bb1f5260180f5f444dd11795a2f' 
  AND token = 'lc9gaDMyVdHGWqCaHfN+WCD3S8p4kBhSwyXGAUAnaS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}