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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '287fc0ca0ea5a8597ac1925f53352678db4e0abcb8e4d5da32d61d74c1c772e4' 
  AND token = '7VRmOVgo5Tb1HoB4x0rLtuk/Ih1g01uxLlZxZ725NsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}