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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '80a5cdf7a4b4da39e2976568a06f1edf434ed184ae90deab8340ae12c506fedf' 
  AND token = 'tSOG2+WKJWyCKHBvRmPHZGrh8VAfDw+xk3TdVkSbGEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}