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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '498bcb22814be1f927328565c5f676eccceba47fd18bfa6b75169b8d587ff205' 
  AND token = 'Fhq63FnJoO3Mv9cZ0td0S0Ou1LMxsVZZMT4ctmoKTvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}