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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '45c35df251e25ff5ac260f27d05c64dc2dce377f745a8467d517726e01db7a94' 
  AND token = 'YQRNmoLoNVoyjY1pWw2nIUto2ZjvrPJ05dSFZ3zCkuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}