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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '0778f244cf71b8b18bbff973917fc17f46f98666301226d895e89b20eccba253' 
  AND token = 'ndHLvxfrg2Zuj2I4lctpPAazQP+1DNAEo/iEXIEdEuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}