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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'f522c9c802afc9efe38fd07d56ab378819e05099afba199c210dba8670321d05' 
  AND token = 'wqS2ATJH1KdqtdNnZ9qY5UfWzIscjG/5rkiAzUEerMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}