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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'c6486afca5f9088013f040860a6b6c1a0a3da5642e16b88a18cfc1a7629cd178' 
  AND token = 'PniUXag++KH/ToSNpSSPO4IDWpTkoB6hHKiHLzostt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}