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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '1318ed4d6e4bf2e6f3251fc7046a361b7f99ca1f654df5d628534e71e96740a5' 
  AND token = 'TjFbLrMKGjFAiQJ+GppEF99VbMg5s5KBUyM5SdDtyWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}