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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '21e80fc2c6b4dcf279cee97767feef0ff3ff098905bfe9526ee1d5ed23976d48' 
  AND token = 'pwV0GcEH7ktES4afzEjRizKxg3j3oH68NPzgVYZMSqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}