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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'a6b309429a65bc6048b24f4216df80acf012a9c6060d9b4a0f360aed16adfda3' 
  AND token = 'JAGB+Ui4s88NHT2TCdYJHd9who3KTFjSU/suSsns8qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}