SELECT 
  q_product_prices.product_id, 
  MIN(
    IF(
      q_product_prices.percentage_discount = 0, 
      q_product_prices.price, 
      q_product_prices.price - (
        q_product_prices.price * q_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  q_product_prices 
WHERE 
  q_product_prices.product_id IN (
    8394, 8395, 8396, 8397, 8398, 8399, 8400, 
    8401, 8402, 8403, 8404, 8405, 8406, 
    8407, 8408, 8409
  ) 
  AND q_product_prices.lower_limit = 1 
  AND q_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  q_product_prices.product_id

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "38.41"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "q_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 16,
        "rows_produced_per_join": 3,
        "filtered": "19.99",
        "index_condition": "(`portal`.`q_product_prices`.`product_id` in (8394,8395,8396,8397,8398,8399,8400,8401,8402,8403,8404,8405,8406,8407,8408,8409))",
        "cost_info": {
          "read_cost": "37.77",
          "eval_cost": "0.64",
          "prefix_cost": "38.41",
          "data_read_per_join": "76"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`portal`.`q_product_prices`.`lower_limit` = 1) and (`portal`.`q_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}

Result

product_id price
8394 309.000000
8395 299.000000
8396 299.000000
8397 299.000000
8398 299.000000
8399 304.000000
8400 304.000000
8401 304.000000
8402 304.000000
8403 380.000000
8404 381.000000
8405 381.000000
8406 381.000000
8407 406.000000
8408 406.000000
8409 406.000000