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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '223a5ea9c9e976d043415959a5c5b7eb45a8129c4bc38e2022afbfabff2ab540' 
  AND token = 'T5zyNjfjIy2ot/gRpRQSy9cGP5PhSWySM2mkjxDMIZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}