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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '4d0d23df8cad69c4b93a4fe8716c772a823d5f2a99a2b4c5ae08befc7889910d' 
  AND token = '8K0HeHlOH0EME2szy0cT/DNN2FZhGhnpIHABcPbb0oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}