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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'ec4345c256a64d2feafb9d77866ac8de4cdfe6b2f37800e0da7e8f6365ff47bd' 
  AND token = 'SVs+xx36wWyIs4AaNSuhELcFEZY3vf7zBlICR3lXtEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}