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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '531ffa64f2702925f19f3ccdc51be96f6edd9c20b8be52fadf2a82a60b063221' 
  AND token = 'sU5ksaANLakU7cdboeBzZEmQARr446rjv0I9Ovq0e7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}