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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '0537b323a6eec92217a27b1d5229dcaef3156c06241b2d6b5bfe1e50078d43eb' 
  AND token = 'V7pksSDkahqXk88u+2A0NxNAgaQvPbGNIc+7xzLtMHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}