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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'df99d4b2fa05d2508aed94902a48a11d5b14252f1d8a176292208455f9d55864' 
  AND token = '+2v8v751uSyiERo8R9lmEJs1UtVXCQMuqo3n55UzQY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}