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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '727ab8cc36be6b6de0bbcbaa48d57c5488982468fe3a0ac241ddb457cb5703c1' 
  AND token = 'llSSthpL2DVvQgLW42qgKtimwL00cmCmXxEm50LtzXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}