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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '21ccece98442934658f16ce5d79553480cc670ce9ea7c938932ae21ba96548f4' 
  AND token = 'q6fmEQ1Z0kMBRQl4Tm+ynoY61yTZnPtw9FEErXLaQxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}