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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'bb25dc1406a1611af8364d207f3f82c563cd2d47ff1142f0d56240cc50830a5c' 
  AND token = 'qU4zlklMgKJ2ngkuj/IINaG9CoRzlIm46jBYokWTkcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}