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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'c79174b13a22a35543f79866990d8c4e5366c0095fb05e244a2ebe07ed457a5e' 
  AND token = 'UUrDuddKHR/yzLB/ScOZxDzPwAcxva3cjLx0WAnXFOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}