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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '50101f01a7e63175ccb1f20e6e7082c420568db8dbc9c1e6e1481b8506b4272f' 
  AND token = 'bQUnm6iRdrZF3UyfTHxUrMpQ/8VBKLn9UFLd/xo+Tv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}