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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'b78307c807f43229b6d0b4bc29bcbdcc9cac3ebc4c71ff51d84718927923b5d1' 
  AND token = 'huNEMqDiI31rgduPhnrz3r5UporkGDUTn3AMAeZV72c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}