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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '43f67b257bb27e243b766f9b131d227f5be2b2043dea036fc9507b0de88ed22c' 
  AND token = 'Q7ilEExz6qNJ5RK4CwpBoNWA2BG/2xcvaeXCc9aEnto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}