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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '2c80f3a96e68bd3442fb8a34e0d304336a2f30e17fb8177f1f25d4fdeb51301d' 
  AND token = 'qf3YwmFSPqqIL8R6zeAYY44Hg67FpJv+XjE6WqTYVKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}