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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '222d6d2a6cae753d899247f2f5dee1136080a5e40285d60b109e933e35957451' 
  AND token = 'jbJnwXu/DyIxj9Xiu4XlI9fmrEfs1e5BUtXP7Hsmc24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}