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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '1a88fde8ef7d33a87911b318e503c568a5f411c228df0b067976fb643c249258' 
  AND token = 'EDn479YF5xZWJ4Hhl0zE10ULaoFh1fIz0tje3Go+KP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}