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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'b2ea3f19a047d72be66c106fec686941810000b2f3b52e2fb37247c7a5037811' 
  AND token = '8Q+Q78/zsDMa13RifMC2ckHlpV6Nxva8XBeYhFz2490=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}