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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '195a2d63073a26dfe2fa5dffc2b4fdb1bd102717f02a362ae1d51935be4585ab' 
  AND token = 'DJipyjMoOF5uD0YylelYqoWixbga4q08jZRDh4rfOzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}