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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'f6c4a640433dff11f526353d467408c9ba9a50d9c806bc07d1cc9ffdcc906f96' 
  AND token = 'q1UUDJZZxUXdrUxEa4+LrxMQFisTbWh5OiTNdQn0CCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}