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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '4b8a95e53c58f52178f1125a91d605d9375c77946f425bac6ddc4b10793da2ee' 
  AND token = 'CGE0r8Fcdlz2IOVbMl8ZQpQRPTuArSVPoz8s29+OzFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}