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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '09282018e08640e97163381302a7e397c7f1c4f0369fd41e9392c27618cdf7cc' 
  AND token = 'v8pWR8zl8aF5d3YcHAxlRW79uU91h3rlodfvGIXQnWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}