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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '78ac5570f163cdfb389ea49b6f0df77ede5b0cc7a6d78fd8268a745bdb2ee7ad' 
  AND token = 'HSzjrc5NOr7NveoM98NMJ2IWLz4HW0y+6TMwNdFqiwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}