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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '081a4c04c7681c616b8561f9f2e26dd227bdb9ad091b7228b41a85a9147f623f' 
  AND token = 'APdHyzvBBrS2eJyDM2HmC+poWGpDyIlBmWaW3b4+TuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}