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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '2ad8f3b384452556c868b72039f717094962aae0cae07a44aabab69de4838aa2' 
  AND token = 'O7FfQRMhD6NgikUw19oeFY5sXaiMGy1P4pnVnBIM8G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}