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SELECT 
  SQL_CALC_FOUND_ROWS products.product_id, 
  descr1.product as product, 
  companies.company as company_name, 
  products.product_type, 
  products.parent_product_id 
FROM 
  q_products as products 
  LEFT JOIN q_product_options_inventory as inventory ON inventory.product_id = products.product_id 
  LEFT JOIN q_product_descriptions as descr1 ON descr1.product_id = products.product_id 
  AND descr1.lang_code = 'en' 
  LEFT JOIN q_product_prices as prices ON prices.product_id = products.product_id 
  AND prices.lower_limit = 1 
  LEFT JOIN q_companies AS companies ON companies.company_id = products.company_id 
  INNER JOIN q_products_categories as products_categories ON products_categories.product_id = products.product_id 
  INNER JOIN q_categories ON q_categories.category_id = products_categories.category_id 
  AND (
    q_categories.usergroup_ids = '' 
    OR FIND_IN_SET(0, q_categories.usergroup_ids) 
    OR FIND_IN_SET(1, q_categories.usergroup_ids)
  ) 
  AND q_categories.status IN ('A', 'H') 
WHERE 
  1 
  AND q_categories.category_id IN (
    2, 3, 4, 101, 102, 107, 114, 118, 130, 134, 
    139, 145, 246, 404, 524, 586, 590, 5, 
    100, 103, 106, 108, 115, 119, 131, 135, 
    140, 146, 247, 525, 591, 10, 39, 104, 
    109, 113, 116, 120, 132, 136, 141, 366, 
    526, 592, 11, 105, 110, 117, 121, 133, 
    137, 142, 400, 527, 593, 111, 122, 124, 
    138, 143, 403, 523, 594, 112, 123, 144, 
    457, 458, 616, 245, 549, 583, 405, 585, 
    432, 577, 578, 589, 617
  ) 
  AND companies.status = 'A' 
  AND (
    CASE products.tracking WHEN 'O' THEN inventory.amount > 0 WHEN 'B' THEN products.amount > 0 ELSE 1 END
  ) 
  AND (
    products.usergroup_ids = '' 
    OR FIND_IN_SET(0, products.usergroup_ids) 
    OR FIND_IN_SET(1, products.usergroup_ids)
  ) 
  AND products.status IN ('A') 
  AND prices.usergroup_id IN (0, 0, 1) 
  AND products.parent_product_id = 0 
GROUP BY 
  products.product_id 
ORDER BY 
  products.timestamp desc, 
  products.product_id ASC 
LIMIT 
  224, 16

Query time 0.12604

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "1989.89"
    },
    "ordering_operation": {
      "using_filesort": true,
      "grouping_operation": {
        "using_temporary_table": true,
        "using_filesort": false,
        "nested_loop": [
          {
            "table": {
              "table_name": "inventory",
              "access_type": "system",
              "possible_keys": [
                "pc"
              ],
              "rows_examined_per_scan": 0,
              "rows_produced_per_join": 1,
              "filtered": "0.00",
              "const_row_not_found": true,
              "cost_info": {
                "read_cost": "0.00",
                "eval_cost": "0.20",
                "prefix_cost": "0.00",
                "data_read_per_join": "976"
              },
              "used_columns": [
                "product_id",
                "amount"
              ]
            }
          },
          {
            "table": {
              "table_name": "q_categories",
              "access_type": "range",
              "possible_keys": [
                "PRIMARY",
                "c_status",
                "p_category_id"
              ],
              "key": "p_category_id",
              "used_key_parts": [
                "category_id"
              ],
              "key_length": "3",
              "rows_examined_per_scan": 82,
              "rows_produced_per_join": 16,
              "filtered": "20.00",
              "using_index": true,
              "cost_info": {
                "read_cost": "111.53",
                "eval_cost": "3.28",
                "prefix_cost": "114.81",
                "data_read_per_join": "43K"
              },
              "used_columns": [
                "category_id",
                "usergroup_ids",
                "status"
              ],
              "attached_condition": "((`portal`.`q_categories`.`category_id` in (2,3,4,101,102,107,114,118,130,134,139,145,246,404,524,586,590,5,100,103,106,108,115,119,131,135,140,146,247,525,591,10,39,104,109,113,116,120,132,136,141,366,526,592,11,105,110,117,121,133,137,142,400,527,593,111,122,124,138,143,403,523,594,112,123,144,457,458,616,245,549,583,405,585,432,577,578,589,617)) and ((`portal`.`q_categories`.`usergroup_ids` = '') or find_in_set(0,`portal`.`q_categories`.`usergroup_ids`) or find_in_set(1,`portal`.`q_categories`.`usergroup_ids`)) and (`portal`.`q_categories`.`status` in ('A','H')))"
            }
          },
          {
            "table": {
              "table_name": "products_categories",
              "access_type": "ref",
              "possible_keys": [
                "PRIMARY",
                "pt"
              ],
              "key": "PRIMARY",
              "used_key_parts": [
                "category_id"
              ],
              "key_length": "3",
              "ref": [
                "portal.q_categories.category_id"
              ],
              "rows_examined_per_scan": 156,
              "rows_produced_per_join": 2558,
              "filtered": "100.00",
              "using_index": true,
              "cost_info": {
                "read_cost": "80.19",
                "eval_cost": "511.68",
                "prefix_cost": "706.68",
                "data_read_per_join": "39K"
              },
              "used_columns": [
                "product_id",
                "category_id"
              ]
            }
          },
          {
            "table": {
              "table_name": "products",
              "access_type": "eq_ref",
              "possible_keys": [
                "PRIMARY",
                "status",
                "idx_parent_product_id"
              ],
              "key": "PRIMARY",
              "used_key_parts": [
                "product_id"
              ],
              "key_length": "3",
              "ref": [
                "portal.products_categories.product_id"
              ],
              "rows_examined_per_scan": 1,
              "rows_produced_per_join": 2269,
              "filtered": "88.70",
              "cost_info": {
                "read_cost": "0.00",
                "eval_cost": "453.84",
                "prefix_cost": "1218.36",
                "data_read_per_join": "13M"
              },
              "used_columns": [
                "product_id",
                "product_type",
                "status",
                "company_id",
                "amount",
                "timestamp",
                "usergroup_ids",
                "tracking",
                "parent_product_id"
              ],
              "attached_condition": "((`portal`.`products`.`parent_product_id` = 0) and (case `portal`.`products`.`tracking` when 'O' then <cache>((NULL > 0)) when 'B' then (`portal`.`products`.`amount` > 0) else 1 end) and ((`portal`.`products`.`usergroup_ids` = '') or find_in_set(0,`portal`.`products`.`usergroup_ids`) or find_in_set(1,`portal`.`products`.`usergroup_ids`)) and (`portal`.`products`.`status` = 'A'))"
            }
          },
          {
            "table": {
              "table_name": "companies",
              "access_type": "eq_ref",
              "possible_keys": [
                "PRIMARY"
              ],
              "key": "PRIMARY",
              "used_key_parts": [
                "company_id"
              ],
              "key_length": "4",
              "ref": [
                "portal.products.company_id"
              ],
              "rows_examined_per_scan": 1,
              "rows_produced_per_join": 226,
              "filtered": "10.00",
              "cost_info": {
                "read_cost": "0.00",
                "eval_cost": "45.38",
                "prefix_cost": "1672.20",
                "data_read_per_join": "1M"
              },
              "used_columns": [
                "company_id",
                "status",
                "company"
              ],
              "attached_condition": "(`portal`.`companies`.`status` = 'A')"
            }
          },
          {
            "table": {
              "table_name": "descr1",
              "access_type": "eq_ref",
              "possible_keys": [
                "PRIMARY",
                "product_id"
              ],
              "key": "PRIMARY",
              "used_key_parts": [
                "product_id",
                "lang_code"
              ],
              "key_length": "9",
              "ref": [
                "portal.products_categories.product_id",
                "const"
              ],
              "rows_examined_per_scan": 1,
              "rows_produced_per_join": 226,
              "filtered": "100.00",
              "cost_info": {
                "read_cost": "0.00",
                "eval_cost": "45.38",
                "prefix_cost": "1717.59",
                "data_read_per_join": "865K"
              },
              "used_columns": [
                "product_id",
                "lang_code",
                "product"
              ]
            }
          },
          {
            "table": {
              "table_name": "prices",
              "access_type": "ref",
              "possible_keys": [
                "usergroup",
                "product_id",
                "lower_limit",
                "usergroup_id"
              ],
              "key": "usergroup",
              "used_key_parts": [
                "product_id"
              ],
              "key_length": "3",
              "ref": [
                "portal.products_categories.product_id"
              ],
              "rows_examined_per_scan": 1,
              "rows_produced_per_join": 226,
              "filtered": "99.95",
              "using_index": true,
              "cost_info": {
                "read_cost": "226.92",
                "eval_cost": "45.36",
                "prefix_cost": "1989.89",
                "data_read_per_join": "5K"
              },
              "used_columns": [
                "product_id",
                "lower_limit",
                "usergroup_id"
              ],
              "attached_condition": "((`portal`.`prices`.`lower_limit` = 1) and (`portal`.`prices`.`usergroup_id` in (0,0,1)))"
            }
          }
        ]
      }
    }
  }
}

Result

product_id	product	company_name	product_type
47884	Beauty Skin Slimming Soap White 130 g	Mohd Hassan Asadi Trading Co.L.L.C	P
47885	Aichun Beauty Black Mask Whitening Complex Black 100 Ml	Mohd Hassan Asadi Trading Co.L.L.C	P
47886	Glysolid Glycerin Cream - 250 Ml All Skin Types	Mohd Hassan Asadi Trading Co.L.L.C	P
47887	Glysolid Glycerin Cream 125 Ml All Skin Types	Mohd Hassan Asadi Trading Co.L.L.C	P
47888	Burnus Glysolid Glycerin Cream Pack - 80 ml	Mohd Hassan Asadi Trading Co.L.L.C	P
47889	Pyary 3-Peice Turmeric Soap For Women	Mohd Hassan Asadi Trading Co.L.L.C	P
47890	Parley Nomarks Anti-Marks Cream With Fruit Extracts 25 G	Mohd Hassan Asadi Trading Co.L.L.C	P
47894	Cantu Shea Butter Coconut Curling Cream	Mohd Hassan Asadi Trading Co.L.L.C	P
46652	Meseta Espresso Italiano Decaffeinato Capsules 50 Grams Buy 1 Get 1	Sell Fast Household Appliances LLC	P
46651	Meseta Espresso Italiano Classico Capsules 50 Grams Buy 1 Get 1	Sell Fast Household Appliances LLC	P
46650	Meseta Espresso Italiano Forte Capsules 50 Grams Buy 1 Get 1 Free	Sell Fast Household Appliances LLC	P
44984	L'Oreal Paris Brow Artist Paradise Pomade Eyebrow - Brunette 2	Bashir Jan Muhammad Trading LLC	P
44985	L'Oréal Paris - Paradise Pomade Extatic 106 Ebony	Bashir Jan Muhammad Trading LLC	P
44986	Eyebrow - Brow Artist Pomade 103 Chatain	Bashir Jan Muhammad Trading LLC	P
44987	L'Oreal Paris Brow Artist Pomade, 106 Ebony, 3g	Bashir Jan Muhammad Trading LLC	P
44988	Brush Set With Case Purple/Gold/Black	Bashir Jan Muhammad Trading LLC	P