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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'a0add7074bc4e2039dfd794869e50e4a43949dce4243ac20a87d313b1a1cfddf' 
  AND token = '0oL/xmx/Lv6DjZjnh5F5uIsz57RSEKkYiwjER23EBMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}