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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'b576ef51c1eb66f55d71bd9f62edfbce8343938295e6e5bb55ae93b8ab9df278' 
  AND token = 'JHqAjKv2nEiLDTDtp8KwKEAd01rpNzRUg4mLXmnr5u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}