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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '6f4ad77651154e75bbea47559abf78311f08e3520f275e5143a80dd5ef0c5636' 
  AND token = 'R3gaShXOz7Swn3v7uv0LGTdO46EEdyL0qjhVcAWW7B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}