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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '0ecd2be4c6cdabc65e1c8783667fd00f658b2b0471bcdbb694b9588f7e8e5435' 
  AND token = 'B4HDcdhaYr1CeoZx0ZLpT+g9+R66XV0uk8kEVIRCIWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}