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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'b27d00b82866364b1bf8d55911ab300ef029f8c8cda7a8d3a66436d01e12143a' 
  AND token = 'MYCc9MHWTlslyHFsvSvMP2to5Ix9+QsS2qaOPf1f6X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}